Exenatide is an example of which anti-diabetic drug class?

Exenatide is an example of which anti-diabetic drug class?

• A. GLP-1 receptor agonists
• B. SGLT-2 inhibitors
• C. Meglitinides
• D. DPP-4 inhibitors

Answer: (A)

Exenatide is a GLP-1 receptor agonist, an incretin mimetic used in type 2 diabetes. By activating GLP-1 receptors, it enhances glucose-dependent insulin secretion from the pancreas and suppresses glucagon, while also slowing gastric emptying and promoting satiety. This combination lowers blood glucose and can aid weight loss. It’s distinct from SGLT-2 inhibitors, which work by preventing glucose reabsorption in the kidneys; meglitinides, which directly stimulate insulin release via closing KATP channels on beta cells; and DPP-4 inhibitors, which raise endogenous GLP-1 by inhibiting its degradation.

Exenatide is a GLP-1 receptor agonist, an incretin mimetic used in type 2 diabetes. By activating GLP-1 receptors, it enhances glucose-dependent insulin secretion from the pancreas and suppresses glucagon, while also slowing gastric emptying and promoting satiety. This combination lowers blood glucose and can aid weight loss. It’s distinct from SGLT-2 inhibitors, which work by preventing glucose reabsorption in the kidneys; meglitinides, which directly stimulate insulin release via closing KATP channels on beta cells; and DPP-4 inhibitors, which raise endogenous GLP-1 by inhibiting its degradation.