For children over age 14 or those with certain immunocompromising conditions, how many HPV vaccine doses are required?

For children over age 14 or those with certain immunocompromising conditions, how many HPV vaccine doses are required?

• A. Two doses
• B. Three doses
• C. Four doses
• D. One dose

Answer: (B)

Dosing depends on age at the start and immune status. For anyone who begins HPV vaccination at age 15 or older, or who is immunocompromised, the recommended plan is three doses given over about six months (0, 1–2 months, and 6 months). The immune response in these groups is not as robust with just two doses, so an extra dose ensures adequate protection. In contrast, starting before age 15 uses a two-dose schedule, and one dose or four doses aren’t part of the standard adult-start or immunocompromised-start regimens. Therefore, for children over 14 or those with certain immunocompromising conditions, three doses are required.

Dosing depends on age at the start and immune status. For anyone who begins HPV vaccination at age 15 or older, or who is immunocompromised, the recommended plan is three doses given over about six months (0, 1–2 months, and 6 months). The immune response in these groups is not as robust with just two doses, so an extra dose ensures adequate protection. In contrast, starting before age 15 uses a two-dose schedule, and one dose or four doses aren’t part of the standard adult-start or immunocompromised-start regimens. Therefore, for children over 14 or those with certain immunocompromising conditions, three doses are required.