For PCOS not desiring pregnancy, which treatment option is commonly used?

For PCOS not desiring pregnancy, which treatment option is commonly used?

• A. Metformin
• B. Spironolactone
• C. Finasteride
• D. Low-dose combined oral contraceptive pill

Answer: (D)

In PCOS where pregnancy isn’t desired, the main goal is to regulate menstrual cycles and lessen hyperandrogenic symptoms while providing contraception. A low-dose combined oral contraceptive pill is commonly used because the estrogen component increases SHBG and decreases free testosterone, while the progestin component suppresses ovarian androgen production and stabilizes the endometrium. This combination helps regularize menses, reduce acne and hair growth, and prevent endometrial hyperplasia. Metformin can be helpful for insulin resistance and weight management and may aid ovulation later if pregnancy is desired, but it isn’t the primary option for symptom control in someone not seeking pregnancy. Spironolactone or finasteride can help with hirsutism but are usually adjuncts to COC due to pregnancy considerations and the need for contraception while using them.

In PCOS where pregnancy isn’t desired, the main goal is to regulate menstrual cycles and lessen hyperandrogenic symptoms while providing contraception. A low-dose combined oral contraceptive pill is commonly used because the estrogen component increases SHBG and decreases free testosterone, while the progestin component suppresses ovarian androgen production and stabilizes the endometrium. This combination helps regularize menses, reduce acne and hair growth, and prevent endometrial hyperplasia. Metformin can be helpful for insulin resistance and weight management and may aid ovulation later if pregnancy is desired, but it isn’t the primary option for symptom control in someone not seeking pregnancy. Spironolactone or finasteride can help with hirsutism but are usually adjuncts to COC due to pregnancy considerations and the need for contraception while using them.