In infertility work-up, which test assesses ovulation status?

In infertility work-up, which test assesses ovulation status?

• A. Tubal Patency: HSG
• B. Progesterone Level on Day 21 ≥5 ng/mL
• C. FSH on Day 3
• D. Estradiol Level on Day 3

Answer: (B)

Mid-luteal progesterone testing is used to confirm that ovulation has occurred. A serum progesterone level measured about 7 days after the LH surge, typically on day 21 of a 28-day cycle, with a value of ≥5 ng/mL supports ovulation and indicates the luteal phase is functioning. If progesterone is low, it suggests anovulation or inadequate luteal function. The other options assess different aspects: tubal patency is about a fallopian tube opening, while FSH and estradiol on day 3 mainly reflect ovarian reserve and follicular activity rather than whether ovulation has happened.

Mid-luteal progesterone testing is used to confirm that ovulation has occurred. A serum progesterone level measured about 7 days after the LH surge, typically on day 21 of a 28-day cycle, with a value of ≥5 ng/mL supports ovulation and indicates the luteal phase is functioning. If progesterone is low, it suggests anovulation or inadequate luteal function. The other options assess different aspects: tubal patency is about a fallopian tube opening, while FSH and estradiol on day 3 mainly reflect ovarian reserve and follicular activity rather than whether ovulation has happened.