Postexposure prophylaxis after exposure to invasive meningococcal disease should be started no later than how many days after exposure?

Postexposure prophylaxis after exposure to invasive meningococcal disease should be started no later than how many days after exposure?

• A. 7 days
• B. 14 days
• C. 21 days
• D. 28 days

Answer: (B)

Postexposure prophylaxis aims to prevent a second meningococcal case by eradicating carriage in close contacts. Because the incubation period can extend up to about two weeks, the preventive treatment should be started as soon as possible and no later than two weeks after exposure. Starting within this window maximizes the chance of preventing illness; delaying beyond that window makes the preventive effect unlikely. Prophylaxis is a preventive measure, not treatment for someone who is already symptomatic, and common regimens include rifampin, ciprofloxacin, or ceftriaxone, chosen based on age and other factors.

Postexposure prophylaxis aims to prevent a second meningococcal case by eradicating carriage in close contacts. Because the incubation period can extend up to about two weeks, the preventive treatment should be started as soon as possible and no later than two weeks after exposure. Starting within this window maximizes the chance of preventing illness; delaying beyond that window makes the preventive effect unlikely. Prophylaxis is a preventive measure, not treatment for someone who is already symptomatic, and common regimens include rifampin, ciprofloxacin, or ceftriaxone, chosen based on age and other factors.