Where do erythema multiforme rashes typically appear?

Where do erythema multiforme rashes typically appear?

• A. Usually on the distal extremities
• B. Primarily on the trunk
• C. Only on the face
• D. Limited to palms and soles

Answer: (A)

Erythema multiforme most often shows target-shaped lesions on the distal extremities, especially the hands and feet, and other acral areas like forearms and legs. This acral distribution is a classic cue for EM and helps distinguish it from rashes that predominantly involve the trunk or other sites. While EM lesions can involve the palms and soles and mucous membranes in more extensive disease, the hallmark pattern is they favor the distal extremities rather than the trunk, face, or being limited to palms/soles only.

Erythema multiforme most often shows target-shaped lesions on the distal extremities, especially the hands and feet, and other acral areas like forearms and legs. This acral distribution is a classic cue for EM and helps distinguish it from rashes that predominantly involve the trunk or other sites. While EM lesions can involve the palms and soles and mucous membranes in more extensive disease, the hallmark pattern is they favor the distal extremities rather than the trunk, face, or being limited to palms/soles only.