Which of the following is NOT a feature of Henoch-Schonlein purpura?

Which of the following is NOT a feature of Henoch-Schonlein purpura?

• A. Hyperglycemia
• B. Purpuric rash on the waist extending to the legs
• C. Arthritis
• D. Abdominal pain

Answer: (A)

Henoch-Schonlein purpura is an IgA-mediated small-vessel vasculitis that most often affects children. The hallmark features include a palpable purpuric rash on dependent areas such as the buttocks and legs, arthritis or arthralgias (often in the knees and ankles), and abdominal pain from GI involvement that can lead to cramping or even intestinal complications. Renal involvement with hematuria or proteinuria can also occur due to IgA deposition in the kidneys. Hyperglycemia is not a feature of this vasculitis and does not fit the typical presentation. The rash, joint pain, and abdominal symptoms align with HSP, while hyperglycemia does not.

Henoch-Schonlein purpura is an IgA-mediated small-vessel vasculitis that most often affects children. The hallmark features include a palpable purpuric rash on dependent areas such as the buttocks and legs, arthritis or arthralgias (often in the knees and ankles), and abdominal pain from GI involvement that can lead to cramping or even intestinal complications. Renal involvement with hematuria or proteinuria can also occur due to IgA deposition in the kidneys. Hyperglycemia is not a feature of this vasculitis and does not fit the typical presentation. The rash, joint pain, and abdominal symptoms align with HSP, while hyperglycemia does not.