Which statement about angiokeratomas is true?

Which statement about angiokeratomas is true?

• A. They are usually asymptomatic
• B. They are typically painful
• C. They always require biopsy
• D. They indicate systemic disease

Answer: (A)

Angiokeratomas are benign skin vascular lesions. They typically appear as small, dark red to blue papules and are usually asymptomatic. They may bleed if injured, but pain is not a defining feature. Biopsy is not routinely needed unless the diagnosis is uncertain or there are concerning features. While a Fabry disease–related form exists (angiokeratoma corporis diffusum) linked to a systemic condition, the common, isolated angiokeratomas do not indicate systemic disease. So the statement that they are usually asymptomatic is the best fit.

Angiokeratomas are benign skin vascular lesions. They typically appear as small, dark red to blue papules and are usually asymptomatic. They may bleed if injured, but pain is not a defining feature. Biopsy is not routinely needed unless the diagnosis is uncertain or there are concerning features. While a Fabry disease–related form exists (angiokeratoma corporis diffusum) linked to a systemic condition, the common, isolated angiokeratomas do not indicate systemic disease. So the statement that they are usually asymptomatic is the best fit.